Prof. Chippada Appa Rao has been working as faculty in Dept. of Biochemistry since 1989. He obtained his Ph.D from University of Madras. He was awarded DBT post doctoral fellowship in IISC, Bangalore and PDF in University of Pennsylvania. He has received UGC Onetime grant in recognition of his research contribution and he has been awarded A.P. Academy of Science fellowship. Under his guidance 24 students were awarded Ph.Ds in Biochemistry. He has published more than 85 papers in International and National Journals and edited 3 books. He has completed 10 research projects funded by UGC, ICMR, and DAE ETC.
He has served several Administrations positions in the University such as Head, Chairman, BOS, Director DOA, Dean University Development, Dean, CDC and Principal S.V.U College of Pharmaceutical Science
General Publications
Beta cell function in insulin treated insulin dependent diabetes patient. Ramachandran, A.; Snehalatha, C.; Mohan, V.; Appa Rao, Ch.; and Viswanathan, M. 1986,1,5, 411- 414. (Impact factor: 3.008)
Oral hypoglycemic agents in the treatment of immunogenic insulin resistance in NIDDM. Ramachandran, A.; Snehalatha,C.; Mohan,V.; Appa Rao, Ch.; Viswanathan. M. Diabetes Metab. 1987, 13, 140-143. (Impact factor: 2.845)
Rapid improvement in insulin sensitivity during glycemic regulation in NIDDM Ramachandran, A.; Snehalatha, C.; Mohan,V.; Appa Rao, Ch.; Vijay Kumar, G.; and Viswanathan, M. J Assoc Physicians India. 1988, 36, 508-510. (Impact factor: Not available)
Effect of storage procedures on insulin antiinsulin complexes in plasma. Snehalatha, C.; Appa Rao, Ch.; Ramachandran, A.; Viswanathan, M. Journal of Diabetic Association of India. 1988, 29, 97-99. (Impact factor: Not available)
Antiinsulin antibodies micro vascular complications of Snehalatha, C.; Appa Rao, Ch.; Rema, M.; Mohan,V.; Ramachandran, A.; Viswanathan, M. Journal of Diabetic Association of India. 1989, 29, 13-16. (Impact factor: Not available)
Role of Antiinsulin antibodies in the causation of Microvascular complications of diabetes mellitus. Appa Rao, Ch.; Snehalatha, FASEB Journal. 1993, 7, 4, 845-5. (Impact factor: 5.48)
Hyper insulinism and insulin sensitivity in non obese offspring of conjugal diabetic parents and individual with IGT and NIDDM. Appa Rao, Ch.; Snehalatha, C. FASEB Journal.1995, 9,4, a749-9. (Impact factor: 5.498)
Hyper insulinism and decreased insulin sensitivity in nonobese healthy offspring of conjugal diabetic parents and individuals with IGT and Appa Rao, Ch.; Snehalatha,C. Ind.J Physiol Pharmacol.1996,40,2,139-145. (Impact factor: Not available)
Herbal Medicine: In the Management of diabetes mellitus. Kameswara Rao, B.; Giri, R.; Kesavulu, M.; Appa Rao, Ch. Manphar Vaidyapatrika, 1997, 1, 4, 5, 33-35. (Impact factor: Not available)
Serum Sialicacid in Elderly, Atheresclerosis. Vijaya, J.; Giri, R.; Subramanyam, ;Appa Rao, Ch. Atherosclerosis. 1997, 134, 1,2, P.175. (Impact factor: 4.467).
Hyperlipidemia, Increased lipid peroxidation and changes in Antioxidant enzymes, Na+- K+-ATPase in Erythrocytes of Type 2 diabetic patients in Andhra Giri, R.; Kesavulu, M. M.; Kameswara Rao, B.; Ramana, V.; Appa Rao, Ch. Indian Journal of Clinical Biochemistry, 1999, 14 ,2, 168-175. (Impact factor: Not available)
Antidiabetic and Hypolidemic effects of Momordica cymbalaria Hook. Fruit powder in Alloxan Diabetic rats. Kameswara Rao, B.; Kesavulu, M. M.; Giri, R.; Appa Rao, Ch. J. Ethnopharmacol. 1999, 67, 103-109. (Impact factor: 3.115)
Changes in serum zinc, sialic acid, glucose and lipid profile in NIDDM. Juturu, V.; Giri, R.; Kesavulu, M.M.; Subramanyam, G.; Appa Rao. Ch. Trace Elements and Electrolytes. 1999, 16,2, 104-108. (Impact factor: 0.333)
Lipid peroxidation and Antioxidant enzyme levels in Type II diabetics with microvascular complications. Appa Rao, Ch.; Kesavulu, M.M.; Kameswara Rao, B.; Giri, R. FASEB Journal. 1999,13,4. (Impact factor: 5.5)
Insulin like effect of sodium ortho vanadate on glycoprotein metabolism in streptozotocin diabetic Giri, R.; Kesavulu, M. M.; Kameswara Rao, B.; and Appa Rao. Ch., J. Biochem. Mol. Biol. & Biophys. 2000, 14, 4, 277-284. (Impact factor: Not available)
Lipid peroxidation and antioxidant enzyme levels in Type 2 Diabetics with microvascular complications. Kesavulu, M.M.; Giri,R.; Kameswara Rao, B.; Appa Rao, Ch. Diabetes & Metabolism. 2000, 26, 5, 387-392. (Impact factor: 3.744)
Effect of oral administration of bark extract of Pterocarpus santalinus on blood glucose level of experimental animals. Kameswara Rao, B.; Kesavulu, M. M.; Giri, R.; Appa Rao, Ch. J. Ethnopharmacol. 2001, 74, 1, 69-74.(Impact factor: 3.115)
Lipid peroxidation and Antioxidant enzymes status in type II Diabetics with coronary Heart Diseases. Kesavulu, M.M.; Kameswara Rao, B.; Giri, R.;Vijaya,J.; Subramanyam, G.; AppaRao, Ch. Diabetes research and Clinical Practice. 2001, 53, 1,33-39.(Impact factor: 2.548)
Hypoglycemic and Antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. Seed extracts in normal and diabetic rats. Kameswara Rao, B.; AppaRao, Ch. Phytomedicine.2001, 8, 2, 88-93. (Impact factor: 3.160)
Antihyperglycemic activity of Momordica cymbalaria in alloxan diabetic
Kameswara rao, B.; Kesavulu, M.M.; Apparao, Ch. J. Ethnopharmacol. 2001, 78, 1, 67-
(Impact factor: 3.115).
Effect of -3 fatty acids on lipid peroxidation and anti oxidant enzyme status in type 2 diabetic patients. Kesavulu, M.M.; Kameswara rao, B.; Apparao, Ch.; Kumar, E.G.T.V.; Harinarayan, C.V. Diabetes & Metabolism . 2002, 28, 20-26. (Impact factor: 3.744)
Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan- diabetic rats.
Kameswara rao, B.; Kesavulu, M.M.; Apparao. Ch. Fitoterapia. 2003, 74, 1-2, 7-13. (Impact factor: 2.216).
Antidiabetic activity of Terminalia pallid in alloxan induced Kameswararao, B.; Renuka Sudarshan, P.; Rajasekhar M.D.; Nagaraju, N.Apparao,Ch. J. Ethnopharmacol. 2003, 85, 1, 169-172. (Impact factor: 3.115)
Sialic acid levels in type 2 diabetics with micro vascular complications. Apparao, Ch.; Kesavulu, M.M.; Kameswara rao, B. Diabetes and Metabolism. 2003, 2686. (Impact factor: 2.845)
Effect of Scoparia dulcis extract on Insulin Receptors in Streptozotocin Induced Diabetic Rats: Studies on Insulin Binding to Erythrocytes. Pari, L.; Latha, M.; Appa Rao, Ch. J Basic Clin Physiol Pharmacol. 2004, 15, 225-240. (Impact factor: Not available)
Effect of vanadate treatment on the histological changes in streptozotocin induced diabetic rats. Giri, R.; Appa Rao, Ch. Indian journal of comparative animal physiology.
2004, 22, 1-7. (Impact factor: Not available)
Pterocarpus santalinus In the Management of Diabetes mellitus. Apparao, Ch.; Kameswara Rao, B.; Rajasekhar, M.D. Proceedings-International Conference on Botanical. 2005, 313-316. (Impact factor: Not available)
Treatment of Diabetes Mellitus: Plant Drugs vs Oral Hypoglycaemic Agents and Insulin.
Kameswara Rao, Badri.; Rajasekhar, M.D.; Sreelatha, A.; Apparao, Ch. In Recent Progress in medicinal Plants. 2006, 14, 279-296. (Impact factor: Not available)
Effect of N-benzoyl-D-phenylalanine and metformin on insulin receptors in neonatal streptozotocin-induced diabetic rats: Studies on insulin binding to erythrocytes. Ashokkumar, N.; Pari, l.; Appa Rao, Ch. Arch Physiol Biochem. 2006, 112, 3, 174-181.(Impact factor: Not available)
Antihyperglycemic activity of leaf callus of Gymnema sylvestre Br.in experimental diabetic rats. Sairam Reddy, P.; Prasad Babu, G.; Kameswara Rao, B.; Appa Rao , Ch.; Ram Gopal, G.In Recent trends in Biotechnology.2006,35-39.(Impact factor: Not available)
Influence of Cassia auriculata flowers on insulin receptors in streptozotocin induced diabetic rats:studies on insulin binding to erythrocytes. L. Pari, P. Murugan.; Appa Rao,Ch. African Journal of Biochemistry Research.2007, 1,7,148-155.(Impact factor: Not available)
Effect of tetra hydro curcumin on insulin receptor status in type 2 diabetic rats: Studies on insulin binding to erythrocytes. Murugan, P.; Pari, L.; Appa Rao, Ch. J.Biosciences.
2008, 33, 1, 63-72.(Impact factor:1.528)
In vitro antioxidant activity of aqueous extract of Syzygium alternifolium seeds. Ramesh babu, K.; Rajsekhar, M.D.; Vinay kumar, K.; Sampathkumar, M.R.; Sameena Fatima, S.K. Apparao, Ch. Journal of Pharmacy and Chemistry. 2009, 3, 1,26-31.(Impactfactor:Notavailable).
Antihyperglycemic and antioxidant effects of Talinum portulacifolium leaf extracts in streptozotocin diabetic rats: A dose-dependent Ramesh Babu, K.; Vinay, K.; Sameena, S.K.; Prasad, S.V.; Swapna, S.; Appa Rao, Ch. Pharmacogn Mag. 2009, 5, 19,1- 10. (Impact factor: 1.112).
Antihyperglycemic and antioxidant activities of active fraction from the aqueous extract of Momordica cymbalaria fruits in Streptozotocin induced diabetic Rajasekhar, M.D,; Ramesh Babu, K,; Vinay, K,; Sampath, M.R,; Sameena, S.K,; Appa Rao, Ch. Pharmacognosy Res. 2009, 1, 6, 352-358. (Impact factor: Not available)
Antidiabetic and antihyper lipidemic activity of ethyl acetate: Isopropanol (1:1) fraction of Vernonia anthelmintica seeds in Streptozotocin induced diabetic rats. Shaik Sameena, F.; Rajasekhar, D.; Vinay Kumar, K.; Sampath Kumar, M.T, Ramesh Babu, K.; Appa Rao, Ch. Food Chem Toxicol. 2010, 48, 2, 495-510. (Impact factor: 2.610)
Isolation and characterization of a novel antihyperglycemic protein from the of Momordica cymbalaria. Rajasekhar, M.D.; Kameswara Rao, B.; Vinay Kumar, ; Ramesh Babu,K.; Shaik Sameena, F.; Sampath Kumar, M.T.; Appa Rao, Ch. J. Ethnopharmacol. 2010, 128, 1, 58-62. (Impact factor: 3.115)
Antihyperglycemic and antihyperlipidemic activities of methanol:water (4:1)fraction isolated from aqueous extract of Syzygium alternifolium seeds in Streptozotocin induced diabetic rats. Ramesh Babu, K.; Rajasekhar, M.D.; Vinay Kumar, K.; Shaik Sameena, F.; Tiruvenkata Kumar, E.G.; Swapna, S.; Ramesh, B.; Appa Rao, Ch. Food Chem Toxicol. 2010, 48, 1078–1084. (Impact factor: 3.997)
Antihyperglycemic and hypolipidemic activities of Setaria italic seeds in STZ diabetic rats. Sireesha,Y.; Ramesh Babu, K.; Nabi, S.A.; Swapna,S.; Appa Rao, Ch. Pathophysiology. 2011, 18, 2, 159–164. (Impact factor: 2.05)
Antihyperglycemic and antioxidant activities of alcoholic extract of Commiphora mukul gum resin in streptozotocin induced diabetic rats. Ramesh, B.; Rasineni, K.; Sreenivasa Reddy, S.; Ramesh Babu, K.; Ramatholisamma, P.; Appa Rao, Ch.; Saralakumari, D. Pathophysiology. 2011, 18, 4, 255- 261. (Impact factor:2.05)
Antihyperlipidemic and antiatherogenic activities of Terminalia pallida. Linn fruits in high fat diet induced hyperlipidemic rats. Sampathkumar, M.T.; Nabi, S.A.; Renuka Sudarshan, P.; Swapna, S.; Appa Rao, J Pharm Bioallied Sci. 2011, 3, 3, 449-452.Impactfactor:Notavailable).
Anti hyperglycemic and antioxidant activities of 3, 3′-(1, 4-phenylene)-bis 2-(1-(benzyl carbonyl)-2, 3-dihydro-1H-pyrrolidine-2-yl)-2-thio-benzoxaphosphinine in STZ induced Diabetic Swapna, S.; Ramesh babu, K.; Nabi, S.A.; Veera narayana Reddy, M.; Suresh Reddy, C.; Appa Rao, Ch. International Journal of Drug Design & Discovery.2012, 3, 1, 677-682. (Impact factor: Not available)
Cinnamic acid as one of the antidiabetic active principle(s) from the seeds of Sygigium alternifolium. Ramesh Babu, ; Nabi, S.A.; Swapna, S.; Appa Rao, Ch. Food Chem Toxicol. 2012, 50, 1425-1431. (Impact factor:3.997)
Hair dye related acute kidney injury-A clinical and experimental study. Sandeep Reddy, Y.; Nabi, S.A.; Apparao, Ch.; Srilatha, C.; Naveen, P.S.; Kishore, C.K.; Sridhar, ; Sivakumar, V. Renal failure. 2012, 34, 7, 880-884. (Impact factor: 1.07)
AntiOxidant activity and GC-MS analysis of Phragmytes vallatoria leaf ethanolic extract. Nagavamsikrishna, A.;Venkataraman,B.; RameshBabu,K.; Apparao,Ch. International research journal of Pharmacy. 2012,3,3,252-254.(Impact factor: Not available)
Ethnobotanical explorations on anti-diabetic plants used by tribal inhabitants of Seshachalam forest of Andhrapradesh, India. Pavani, M.; Sankara Rao, M.; Mahendra Nath, ; Apparao, Ch. Indian Journal of Fundamental and Applied Life Sciences.2012,2, 3, 100-105.(Impact factor: Not available)
Isolation, purification, structural characterization and functional elucidation of novel antihyperglycemic compound from the bark of Pterocarpus santalinus. Vinay kumar, k.; Kameswara Rao, ; Rajasekhar M.D.; Apparao Ch. The FASEB Journal. 2012;26: lb536. (Impact factor: 5.498)
Antidiabetic and anti oxidant activities of Piper longum root aqueous root extract in STZ induced diabetic rats. Nabi, A.; Suban Ali, M.D.; Rajesh, N.; Krishna Tilak, T.; Appa Rao, Ch. Journal of Pharmacy and chemistry.2012, 6, 3, 30-35. (Impact factor: Not available)
Anti hyperglycemic and antioxidant effects of Pennisetum glaucum seed extracts in STZ induced diabetic rats. Venkata Prasad, ; Rajesh, N.; Swapna, S.; Appa Rao, Ch. Journal of Pharmacy and chemistry.2012, 6, 3, 36-42. (Impact factor: Not available)
Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats. Nabi, A.; Ramesh babu, K.; Swapna, S.; Krishna Tilak, T.; Jyothikumar, M.V.; Apparao, Ch. BMC Complement Altern Med. 2013, 13, 1,37.(Impact factor: 2.288)
Synthesis, spectral characterization and antioxidant activity studies of a bidentate Schiff base, 5-methyl thiophene-2-carboxaldehyde-carbohydrazone and its Cd(II), Cu(II), Ni(II) and Zn(II) complexes. Harinath, Y.; Harikishore Kumar Reddy, D.; Naresh Kumar, B.; Apparao, Ch.; Seshaiah, K. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2013,101,264-272.(Impactfactor:2.880)
Anti hyperglycemic and anti hyperlipidemic activities of 2-(4-[(2-hydroxybenzyl) amino]- phenyl amino- methyl) – phenol in STZ induced diabetic rats. Swapna, S.; , Ramesh Babu, K.; Nabi, A.; Rajesh, N.; Prasad, S.; Suresh Reddy, C.; Apparao, Ch. Eur J Med Chem. 2013, 66, 400-406. (Impact factor: 4.816)
Antihyperglycemic and antihyperlipidemic activity of MCy protein. Kameswara Rao, B.; Dilip Rajasekhar, M.; Vinay Kumar, K.; Kumar, E.G.T.V.; Apparao, Ch. The FASEB journal. 2013, 27, lb533. (Impact factor: 5.498)
Synthesis and antioxidant activity of styryl sulfonylmethyl1,3,4-oxadiazoles,pyrazolyl/isoxazolyl-1,3,4oxadiazoles.MallikarjunaReddy,G.Muralikrishna,;Padmavathi,V.;Padmaja,A.;Krishna Tilak, T. Appa Rao, Ch. Chem Pharm Bull.2013, 61, 12, 1291-7. (Impact factor: 1.258)
Synthesis and Spectral Characterization of Nickel (II) and Copper (II) Complexes of 4- Chlorobenzaldehydethiosemicarbazone (CBTSC) and Evaluation of Antioxidant Activity. Asha Kumar, V.; Sarala, Y.; Jyothi Kumar, M.V.; Sivasankar Reddy, M.; Varada Reddy, A.; Appa Rao, Ch. Res J Pharm Biol Chem 2014, 5, 5,96-102. (Impact factor: 0.25)
In -vitro and In-vivo Studies on the Antidiabetic Activity of Stem Bark of Homalium zeylanicum in STZ Induced Diabetic Rajesh, N.; Venkata Prasad, S.; Nabi, S.A.; Swapna, S.; Prabhakar, Y.K.; Subhan Ali, Md.; Appa Rao, Ch. Asian Journal of Biochemical and Pharmaceutical Research. 2014, 4, 3, 76-90. (Impact factor: Not available)
Ultrasonicated, nano-ZnO catalyzed green synthesis of α-hydroxyphosphonates and their antioxidant activity. Thaslim Basha, S.K.; Rasheed, S.; Chandra Sekhar, K.; Naga Raju, C.; Subhan Ali, Md.; Appa Rao, Ch. Phosphorus Sulfur Silicon Relat Elem. 2014, 189:1–11. (Impact factor: 0.674)
Antihyperlipidemic activity of the stem bark of Boswellia ovalifoliolatain high fat diet fed rats. Saritha, ; Prabhakar, Y.K.; Subhan Ali, Md.; Nabi, S.A.; Jyothi Kumar, M.V.; Rajesh, N.; Appa Rao, Ch. International Journal of Medicinal Plants Photon. 2014, 107,572-576. ( Impact factor: 4.18)
Evaluation of Anti-Hyperglycemic activity of Narengi crenulata leaf in STZ induced Diabetic Ramya, N.; Peddanna, K.; Prabhakar, Y.K.; Apparao, Ch. Asian Journal of Biomedical and Pharmaceutical Sciences. 2014, 4, 39, 35-39. (Impact factor: 0.96)
Novel hetero aryl phosphonicdiamides PTPs inhibitors as anti-hyperglycemic Chandra Sekhar, K.; Rasheed, S.; Madhava, G.; Jyothi Kumar, M.V.; Nanda Kumar, Y.; Appa Rao Ch.; Naga Raju, C. DARU Journal of Pharmaceutical Sciences. 2014, 22:76. (Impactfactor:1.638).
Synthesis and antioxidant activity of a new class of sulfone/sulfonamide-linked bis (oxadiazoles), bis (thiadiazoles), and bis (triazoles). Padmaja, ; Devanaboina, P.; Sravya, G.; Mallikarjuna Reddy, G.; Jyothi Kumar, M.V.; Appa Rao, Ch. Medicinal Chemistry Research: 1-1. (Impact factor: 1.607)
Phytochemical screening and antihyperglycemic activity of Heliotropium indicum whole plant in Streptozotocin induced diabetic rats. Subhan Ali, Md.; Nabi, S.A.; Saritha, M.; Krishna Tilak, ; Jyothi Kumar, M.V.; Appa Rao, Ch. Journal of Applied Pharmaceutical Science. 2014, 4, 12, 065-071. (Impact factor: Not available)
Antihyperlipidemic and Biochemical Activities of Mcy Protein in Streptozotocin Induced Diabetic Marella, S.; Maddirela, D.R.; Badri, K.R.; Jyothi Kumar, M.V.; Appa Rao, Ch. Cellular Physiology and Biochemistry. 2015, 35, 4, 1326-1334. (Impact factor: 5.5).
Bhaskara Reddy, M. V., Srinivasulu, D., Peddanna, K., Apparao, C., & Ramesh, P. (2015). Synthesis and antioxidant activity of new thiazole analogues possessing urea, thiourea, and selenourea functionality. Synthetic Communications, 45(22), 2592-2600. (IF-1.065)
Kumar, M. J., Prabhakar, Y., Saritha, M., Tilak, T. K., Nabi, S. A., Ali, M. S., & Rao, C. A. (2016). Effect of flavonoid rich fraction of Andrographis echioides in streptozotocin-induced diabetic rats. J Pharm Chem, 1(10), 16-20.
Marella, S., Maddirela, D. R., Kumar, E. G. T. V., Tilak, T. K., Badri, K. R., & Chippada, A. (2016). Mcy protein, a potential antidiabetic agent: evaluation of carbohydrate metabolic enzymes and antioxidant status. International journal of biological macromolecules, 86, 481-488. (IF-3.909)
Reddy, K. M. K., Santhisudha, S., Mohan, G., Peddanna, K., Rao, C. A., & Suresh Reddy, C. (2016). Nano Gd2O3 catalyzed synthesis and anti-oxidant activity of new α-aminophosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements, 191(6), 933-938.
Tilak, T. K., Nabi, S. A., Krishna, D. P. M., Saritha, M., & Rao, C. A. (2016). Antidiabetic and Antioxidant Activities of Polyherbal Formulation in STZ Induced Diabetic Rats. Pharm. Chem, 9(3), 9-14. (IF-0.679)
Kotha, P., Badri, K. R., Nagalapuram, R., Allagadda, R., & Chippada, A. R. (2017). Anti-Diabetic Potential of the Leaves of Anisomeles malabarica in Streptozotocin Induced Diabetic Rats. Cellular Physiology and Biochemistry, 43(4), 1689-1702. (IF-5.5)
Vadabingi Nagalakshmammaa , Pulluru Hari Babua , Kollu Umapriyab , Chamarthi Naga Rajub , Allagadda Rajasekharc , Chippada Apparaoc and P. V. ChalapathiC. Synthesis, characterization and evaluation of antimicrobial and antioxidant activities of new sulfonamide and carbamate derivatives of 3-(trifluoromethyl)-5,6,7,8-tetra hydro-[1,2,4]- triazolo(4,3-α)-pyrazine (sitagliptin intermediate). ejbps, 2017, Volume 4, Issue 12 809-819.
Gudi, Y., Gundala, S., Venkatapuram, P., Adivireddy, P., Chippada, A. R., & Allagadda, R. (2017).Synthesis and Antioxidant Activity of a New Class of Pyridinylcarbamoylmethyl Pyrrolyl/Pyrazolylcarboxamides. Journal of Heterocyclic Chemistry, 54(6), 3498-3509. (IF-1.141)
Sreelakshmi, P., Santhisudha, S., Reddy, G. R., Subbarao, Y., Peddanna, K., Apparao, C., & Reddy, C. S. (2018). Nano-Cuo–Au-catalyzed solvent-free synthesis of α-aminophosphonates and evaluation of their antioxidant and α-glucosidase enzyme inhibition activities. Synthetic Communications, 48(10), 1148-1163. (IF-1.377)
Apparao Chippada, Peddanna Kotha, Rajasekhar Allagadda and Kameswara R.Badri. Antihyperglycemic Activity of Asparagus gonoclados Root Tubers in Streptozotocin induced Diabetic Rats. 20 Apr 2018; 841.8. The FASEB journal. (IF-5.498).
Rajasekhar, A., Peddanna, K., Appa Rao, Ch. (2018). In vitroanti-oxidant activity and acute toxicity, of ethanol extract of root tubers of Asparagus gonoclados. Inter journal of Biology Res, Vol-3, page: 52 – 56.
Rajasekhar, A., Peddanna, K., Vedasree, N., Munirajeswari, P., Nagaraju, N., Badri, K. R., & Chippada, A. R. (2019). Antidiabetic activity of root tubers of Asparagus gonoclados Baker in streptozotocin induced diabetic rats. Journal of Ethnopharmacology, 242, 112027, 1-9.
Kotha, P., Marella, S., Allagadda, R., Badri, K. R., & Chippada, A. R. (2019). Evaluation of biochemical mechanisms of anti-diabetic functions of Anisomeles malabarica. Biomedicine & Pharmacotherapy, 112, 108598, 1-9.
Chippada Appa Rao, Nalluri Vedasree, Kotha Peddanna, Allagadda Rajasekhar and Kameswara Rao Badri. Antidiabetic Activity of Root Tubers of Cyanotis tuberosain Streptozotocin Induced Diabetic Rats. Abstract Number: lb46, Volume 33, Issue 1_supplement 01 Apr 2019.The FASEB journal.
Shaik Mahammad Sadik,Sarva Santhisudha,Gundluru Mohan,Nadiveedhi Maheshwara Reddy,Poola Sree Lakshmi,Allagadda Rajasekhar,Chippada Appa Rao,Cirandur Suresh Reddy., (2019). Palladium acetate-catalysed one-pot green synthesis of bis α-aminophosphonates. Research on chemical intermediates, 45 (3), pp 1401–1420.
Settypalli, T., Chunduri, V. R., Maddineni, A. K., Begari, N., Allagadda, R., Kotha, P., & Chippada, A. R. (2019). Design, synthesis, in silico docking studies and biological evaluation of novel quinoxaline-hydrazide hydrazone-1, 2, 3-triazole hybrids as α-glucosidase inhibitors and antioxidants. New Journal of Chemistry, 43(38), 15435-15452.
Poola, S., Shaik, M. S., Sudileti, M., Yakkate, S., Nalluri, V., Chippada, A., & Cirandur, S. R. (2020). Nano CuO–Ag‐catalyzed synthesis of some novel pyrano [2, 3‐d] pyrimidine derivatives and evaluation of their bioactivity. Journal of the Chinese Chemical Society.
Tellamekala, S., Gundluru, M., Sarva, S., Nadiveedhi, M. R., Sudileti, M., Allagadda, R., & Cirandur, S. R. (2019). Meglumine sulfate-catalyzed one-pot green synthesis and antioxidant activity of α-aminophosphonates. Synthetic Communications, 49(4), 563-575.
Shaik, M. S., Nadiveedhi, M. R., Gundluru, M., Poola, S., Allagadda, R., Chippada, A. R., & Cirandur, S. R. (2020). Green synthesis of diethyl ((2-iodo-4-(trifluoromethyl) phenyl) amino)(aryl) methyl) phosphonates as potent α-glucosidase inhibitors. Synthetic Communications, 50(4), 587-601.
Konda, P. Y., Marella, S., Natava, R., & Chippada, A. (2020). Diabetes affects hepatic and renal glycoproteins: effect of Boswellia ovalifoliolata on glycoproteins proportions in diabetes induced hepatic and renal injury. Journal of Diabetes & Metabolic Disorders, 1-10.
Konda, P.Y., Nagalapuram, R., Venkateswarlu, J. K. M., Mohammad, S. A., & Chippada, A.R. (2020). Pathophysiology of STZ-induced pancreatic β cell injury and dysfunction: traditional role of Boswellia ovalifoliolata Bal. & Henry on diabetes and dyslipidemia. Comparative Clinical Pathology, 1-11.
Sankaran, K. R., Oruganti, L., Ganjayi, M. S., Chintha, V., Muppuru, M. K., Chippada, A. R., & Meriga, B. (2021). Bauhiniastatin-1 alleviates diet induced obesity and lipid accumulation through modulating PPAR-γ/AMPK expressions: In-vitro, in-vivo and in-silico studies. Page No:1-25.
Sankaran, K. R., Ganjayi, M. S., Oruganti, L., Chippada, A. R., & Meriga, B. (2021). A bioactive fraction of Pterocarpus santalinus inhibits adipogenesis and inflammation in 3T3-L1 cells via modulation of PPAR-γ/SREBP-1c and TNF-α/IL-6. 3 Biotech, 11(5), 1-10.
Kotakadi, V. S., Gaddam, S. A., Kotha, P., Allagadda, R., Rao Ch, A., & DVR, S. G. (2021). Bio-inspired multifunctional zinc oxide nanoparticles by leaf extract of Andrographis serpilifolia and their enhanced antioxidant, antimicrobial, and antidiabetic activity—A 3-in-1 system. Particulate Science and Technology, 1-15.
Vedasree, N., Peddanna, K., Rajasekhar, A., ParthaSarathi, C., Munirajeswari, P., Sireesha, Y., & Chippada, A. R. (2021). Efficacy of Cyanotis tuberosa (Roxb.) Schult. &Schult. f. root tubers active fraction as anti-diabetic, antihyperlipidemic, and antioxidant in Streptozotocin-induced diabetic rats. Journal of Ethnopharmacology, 114856.
Books
- Antidiabetic activity of Heliotropium indicum, Chippada Appa Rao, Subhan Ali, LAMBERT, Academic publishing, 2020.
- Anti-diabetic activity of Boswellia ovalifoliolata & Henry, Chippada Appa Rao, Y.K.Prabhakar, LAMBERT, Academic publishing, 2020.
- Anti-diabetic activity of Anisomales Malabarica, Chippada Appa Rao, Peddanna Kotha, LAMBERT, Academic publishing, 2019.
- Treatment of Diabetes Mellitus: Plant Drugs vs Oral Hypoglycaemic Agents and Insulin. Kameswara Rao, Badri.; Rajasekhar, M.D.; Sreelatha, A.; Apparao, Ch. In Recent Progress in medicinal Plants. 2006, 14, 279-296.
- Antihyperglycemic activity of leaf callus of Gymnema sylvestre Br.in experimental diabetic rats. Sairam Reddy, P.; Prasad Babu, G.; Kameswara Rao, B.; Appa Rao , Ch.; Ram Gopal, G.In Recent trends in Biotechnology.2006,35-39.
Research interest
Endocrinology, Clinical biochemistry, Diabetes mellitus, Medicinal plants with anti diabetic activity
Research projects
Research Projects completed
Major:
“Biochemical studies on the anti diabetic activity of root tuber of Asparagus gonoclados”. ICMR, 2015-2018, Rs.35,00,000/-
UGC-Onetime Grant, 2015 -17, 7,00,000/-
Biochemical studies on Antidiabetic activity of Wrightia tinctoria in STZb Induced diabetic rats. ICMR, 2014-17, Rs.13,99,800/-
Bioremoval and recovery of heavy metals from aqeous medium by Chemically modified biomass, BRNS, 2012-15, Rs.24,90,000/-
Effect of Gamma Irradiation on the Biochemical, Microbiological and Organoleptic properties in Mango pulp and Wine. DAE-BRNS, 2011-14, 20,84,000/-
Biochemical studies on antidiabetic activity of fruits of Momordica cymbalaria. UGC, 2010-13, Rs.10,23,800/-
“Biochemical studies on the antidiabetic activity of the fruits of Terminalia pallida in Streptozotocin induced diabetic rats”. ICMR, 2006-09, Rs.7,34,173/-
Biochemical studies on Antidiabetic activity of Syzigium alternifolium ICMR, 2005-08, Rs.5,25,566/-
Isolation and Characterization of Active principles(s) from the bark of Pterocarpus santalinus. UGC, 2005 -07, 12,00,000/-
Minor:
Lipids and lipoprotein profiles in microvascular complications of diabetesmellitus1995- 1997 UGC, Rs.13,000/-
Conference
Conferences / Workshops Organized:
UGC – HRDC – SVU –Refresher Course in Life sciences, S.V.University, Tirupati from 12-11-2018 to 18-12-2018,
UGC – HRDC – SVU –Refresher Course in Life sciences, V.University, Tirupati from18-08-2016 to 07-09-2016
Science Academies’ Lecture workshop on “Advances in Biology and Biotechnology” at V.University,Tirupati from 2nd to 4th April 2014.
Refresher Course in Biochemistry (for college and university teachers) of UGC Academic Staff College, S.V.University, Tirupati, from 20th December 2004 to 8th January 2005.
National conference on “Trends in Biological Chemistry” 26-28 December 2003 at S.V.University, Tirupati.
Workshops / Conferences/Seminars Attended
Orientation programme for college and university teachers conducted by Academic
Staff College, S.V.University, Tirupati, from 19.8.1991 to 14.9. 1991.
Indo-US workshop on the Application of Molecular biology techniques in Reproductive Biology, conducted by Centre for Reproductive Biology and Molecular Endocrinology, Indian Institute of Science, Bangalore, from 8-17 February 1993.
Workshop on Diet and Diabetes organized by Nutrition Society of India, Tirupati chapter, Dept. of Home science and Health center, S.V.University, Tirupati, 11.March.1993.
65thAnnual session of National Academy of Sciences, India, at S.V.University, Tirupati from 3-5 November 1995.
Symposium on Recent Trends in Biochemistry conducted by Dept. of Biochemistry, S.V.University, Tirupati from 18-19 October 1995.
Refresher course in Biochemistry conducted by Academic Staff College and Dept.of Biochemistry, University of Madras, from 22.01.1996 to 12.02.1996.
Silver jubilee Seminar on Recent Advances in Biochemistry and Molecular Biology and XXIII Annual Conference of Indian Immunological Society conducted by Andhra University, Visakhapatnam, from 12-15 December 1996.
International Symposium on Free Radicals in Medicine and Biology, conducted by R.N.T.Medical College, Udaipur, from 22-24 September 1997.
Refresher course in Biochemistry, conducted by UGC-Academic Staff College, S.V.University, Tirupati, from 24.7.2000 to 12.8.2000.
Refresher course in Value Education, conducted by UGC-Academic Staff College, S.V.University, Tirupati, from 11.11.2002 to 30.11.2002.
International conference on Promotion and Development of Botanicals with International Coordination. Exploring quality, Safety, efficacy and regulations. Organized by Jadavpur University, Kolkata, Drug Information Association, USA and Indian Institute of Chemical Biology, Kolkata, from 25-26, February 2005.
International conference on Ethno pharmacology and Alternative medicine and Annual Conference of National Society of Ethnopharmacology.organized by Amala Cancer Research Centre, Thrissur, Kerala, from 20-22, January 2006.
UGC sponsored national workshop/conference on Recent Trends in Biochemistry and Biotechnology with special reference to Natural Products in Health organized by Dept.of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, from 24-26, February 2006.
UGC sponsored national conference on Diabetes mellitus and Cancer , Dia Can 2007 Organized by Dept.of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, 15-16 Dec.2007.
SFRR Satellite India 2008 Conference, organized by Dept.of Biochemistry,All India Institute of Medical Science,New Delhi from 11-12 Feb 2008.
Application and impacts of chemicals in day to day life in particular to pharmaceuticals an Agriculture.organized by SVRK Govt.Degree College, Nidadavolu, 17-18 July 2009.
National seminar on influence of medicinal plants on human life. Organized by Dravidian Univeristy, Kuppam.19-20 August 2011.
Trendys 2011 in Biochemistry. 18thconference on Biochemistry and Molecular Biology concepts. Dept.of Biochemistry, S.V.University, Tirupati.18-19 November 2011.
International Seminar on Emerging threats and challenges to Biodiversity: Policy framework for sustainable management. Dept. of Botany,S.V.University, Tirupati.2-4 March 2012.
International symposium on Environmental impacts, Health implications, and Therapeutic approaches (ISEHT-2012) a special symposium on water quality and aquatic Biotechnology. Organized by Vikram simhapuri University,Nellore.15-17 July 2012.
National seminar on “Present perspectives of bioactive molecules and biotechnology”organized by Dept.of Biochemistry, Andhra University, Vishakapatnam from 30-31 May2012.
International conference on human health and therapeutic challenges organised by department of Virology, Sri Venkateswara University, Tirupati, A.p, India from December 20-22, 2012.
International conference on role of plant biochemistry and biotechnology in food and nutritional security. Organized by Dept.of Biochemistry, S.V.University, Tirupati. 11-14 December 2013.
National Conference on Conservation of Eastern Ghats, organized by Sri Venkateswara University, Tirupati, from 4th and 5th December 2014.
International Conference on Environmental Conservation and Human Health-Challenges and Strategies (ICECH-2016), Organized by Dept.of Zoology, S.V.University, Tirupati. From 21 to 23 December 2016.
National Cinference on Emerging trends in Agrinanotechnology, AGRINANO -2017, 2nd and 3rd November 2017, organized by Acharya N.G.Ranga Agricultural University and Society of Agrinanotechnology.
104th Indian Science Congress-Convener of New Biology Section at S.V.University,Tirupati,3rd -7th January 2017
International Conference on Herbal and Natural components as the future of pharmacology”.7th Annual meet of the National society of Ethnopharmacology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, 27th February to 1st March 2017.
International Conference on Diabetes and phytotherapy (ICDP-2017), 18th – 20 August, Department of Biochemistry & Biotechnology, Annamalai University.
Nurturing Pharmaceutical and biosciences embarking towards interaction of education, research and drug safety. SVU college of pharmaceutical sciences, S.V.University,Tirupati on 7-10-2017.
Aquaculuture production & biodiversity conservation and environmental toxicology. Dept of Zoology, S.V.University,Tirupati from 30th to 31st August 2017.
Innovations and future challenges in Biotechnology.Dept.of. Biotechnology, S.V.University, Tirupatifrom 26-28 March 2018.
Modern techniques in Molecular biology DBT project (RRSFP) programme, from 31st may to 4th june 2019, in College of pharmaceutical sciences, S.V.University, Tirupati.
Biomedical innovations and small business opportunities, from 22-01-2020 to 23-01-2020 SVIMS, Tirupati.
8th Convention of Society for Ethnopharmacology, India & National Seminar on “Ethnopharmacology for wellness: Tradition to Translation” on December 10, 2021 at CSIR-IICB, Salt Lake Campus, Kolkata
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