Dr. P. Jacob Doss is a Professor in Zoology, S.V.University, Tirupati. He is specialized in Arachnid Neurobiology; Neurotoxicology and Neuroethology. Successfully guided 29 Ph.D’s, and 11 M.Phil’s. He was awarded FIPS Travel Grant to Malaysia in 2002.Completed 4 UGC Projects, Published 80 papers, and written 2 books on one Scorpions, and another book on Snake Biology. Made significant contributions in neurobiology and behavior in the black Scorpion, Heterometrus fulvipes, by identifying different Sensory and Motor neurons in the Central Nervous System with cobalt chloride back filling technique. Currently he is actively involved in Pesticide toxicology, their biotransformation, detoxification mechanism and histopathology with Light and Scanning Electron Microscopy in a mammalian model. Presently working with Pharmacology of drugs, therapeutic treatment of pesticide poisoning and rational use of antidote treatments in clinical investigations. He is the member of Institutional Animal Ethical Committee, Dravidian University, Kuppam, He is one of the members in Board of Studies in Zoology in Bangaloore University and Gulberga University, Andhra University, Osmania University, Kakataiya University, Pondicherry University, Krishna University and Vikramasimha puri University. He was Coordinator to Bioinformatic and DST-FIST and Deputy Coordinator to UGC-SAAP. He also served as Deputy warden and warden for S.V.U. Hostel for Men. Presently he is the Coordinator DDE, Zoology and continuing as a Head, Department of Zoology for second Time. He is the member for Thesis evaluation committee and also for Local Purchasing Committee.
General Publications
- Sasira Babu, K. Kasaiah, A and Jacob doss, P. (1991). Cuticular receptors in the scorpion Heterometrus fulvies. Zool. Soc. India. 42 (1&2): 1-16.
- Sasira Babu, K. Jacob doss, P. Ravinder Rao, B and Sekhar, V. (1993). Central projections primary afferent fibers from a single hair sensillum in the scorpion Heterometrus fulvipes, (C.L Koch, 1983) Ind. Expt. Biol, 31:231-234.
- Babu, K. S and Jacob doss, P. (1994). Central afferent path way of long hair sensilla in the ventral nerve cord of the Indian black scorpion Heterometrus fulvipes, Koch. Comp. Physiol a 174.
- Jacob doss, P. Usha devi, M. Reddy, G. K. and Rajeswara rao, M. (1998) Effect of imidacloprid on rat brain nitrogen synthase activity in vitro J. Comp Animal Physiol.16:20-21.
- Rajeswara Rao, M. Vijayakumari, K. Jacob Doss, P. Vijaya, P. and Vijaya Bharathi, P. (2001). Fructose 1,6 diphosphate mitigates CC14 suppressed nitiric synthase activity in rats. J. Expt. Biol. 39:68-69.
- Medhini, J. Goergeena Kumari, P. Nagi Reddy, P. Mamatha, D. M. Poornima, P. S. Jacob doss, P. Vijayakumari, K and Rao, M. R. (2001). Impact of phenthoate on certain aspects of ammonia and nitrogen metabolism of the fresh water snail, Lymnea luteola. J. Comp. Animal Physiology. 19:11-13.
- Vijaya, P. Raju, A. H. H. Reddy, K. R. Mamatha, D. M. Doss, P. J and Rao. M. R. (2002). Impact of chlordecone on the lipid metabolic profiles of mulberry (Morus albe leaf). J. Sericulture.41:41:57-58.
- Jacob doss, P. Nagarjuna, A. Kishander. N. Dayanand,Y and Dayaker, Y. (2005). Effects of Cephalothroracic nerve mass extracts and haemolymph on spontaneous activity in Heterometrus fulvipes, J.Comp.Animal Physiology. Vo.23:32-40.
- Sudhkar Reddy, P. Nagalakshmamma, K. Nagi Reddy, P. Govinda Reddy, K. Ravi, B. Venkateswarlu, K. Malliswari, M. Gerogeena Kumari, P. Jacob doss, P and Rajeswara Rao, M. (2005). Impact of carbon tetrachloridfe on rat brain nitric oxide synthase activity in vitro. J. Comp. Animal Physiology. Vol. 23:66- 68.
- Sudhkar Reddy, P. Govinda Reddy, K. Nagalakshmamma, K. Nagi Reddy, P. Ravi, B. Venkateswarlu, K. Gerogeena Kumari, P. Malliswari, M. Vijayakumari, K. Jacob doss, P and Rajeswara Rao, M. (2005). Carbontetrochloride induced changes of mammalian cellular nitric oxide synthase activity in vitro. J. Comp. Animal Physiology. Vol. 23:22-23.
- Samson Raju, C. Jacob doss, P. Venkatesulu, P. Nagarjuna, A. Jayantha Rao, K. (2006). Effect of sodium selenite on protein metabolism in a fish Tilapia mossambica. Vol 7(1):21-25.
- Anil kumar, D. H. M. S. Nagarjuna, A. Jacob Doss, P and Jayantha Rao, K. (2006). Effect of aldrin an Organo chlorine compound on albino rat with special Reference to ATPase levels. J. Natcon.18(1)77-85.
- Jacob doss, P. Nagarjuna, A. Suhasini, N. Savithri, Y. Dayanand, Y. Rajeswara Rao, M. (2006). Impact of Monocrotophos on albino rat neuronal nitric oxide synthase activity in vitro. J. Natcon .18(2):231-236.
- Anil Kumar, D. H. M. S. Daniel, R. Jacob Doss, P and Jayantha Rao, K. (2006). Bioreactability of pharmaceutical waste using anaerobic batch reactor. J. Comp. Animal Physiology. Vol.24(2):45-51.
- Jacob Doss, P. Ramanaiah, S. Nagarjuna, A. Suhasini, N. Savithri, Y and Rajendra Prasad, S. (2007). Effect of cypermethrin on various tissues in fresh water edible fish Labeo rohitha with special reference to biochemical parameters. Aquacult.Vol .8 (1): 69-77.
- Jacob Doss, P. Ramanaiah, S. Nagarjuna, A. Suhasini, N. Savithri, Y and S. Rajendra Prasad (2007). Toxicity of cypermethrin on brain and liver of fresh water edible fish Labeo rohitha with special reference to biochemical parameters. Indian Journal .of Environmental Science. 11(1):23-27.
- Narasimha Rao.C, S. Rajendra Prasad, P. Ravi Sekhar, Y. Savithri and P. Jacob Doss (2007). Impact of corticosterone on carbohydrate metabolism of silkworm larvae Bombyx mori., Natcon 19(2): 307 – 312.
- Rajendra Prasad, S. Nagarjuna, A. Siraj Mohiyuddin, S. Narasimha Rao, Kishandar, N and P. Jacob doss (2007). Assessment of Behavioraltolerance during the repeated exposure of chlorpyrifos in albino rats.Indian Journal of comparative animal physiology. Vol 25(1): 25 – 32.
- A, Rajendra Prasad, S. Siraj Mohiyuddin, S. Jaya kumar, R.Savithri, Y and P. Jacob Doss. (2008). Response of cypermethrin intoxication- induced stress in haematological profile of mammalian model albino rat. Asian Journal of Microbiology, Biotechnology and Environmental Sciences. Volume no. (3):547-550.
- A, Rajendra Prasad, S., P. Ravi Sekhar, S. Siraj Mohiyuddin, P.Jacob Doss (2008). Alterations in protein metabolic profiles in gastrocnemius muscle tissue of rat during cypermethrin toxicosis. Journal of Indian society of Toxicology. Vol. 4: 17-21.
- Anil Kumar, D.H.M.S.R. Daniel, Jacob Doss, P and Jayantha Rao (2008). Production of Biosurfactant for the degradation of recalcitrant pollutant using different nutrient sources. Indian Journal of comparative animal physiology. Vol 26(1): 31 – 37.
- Jacob Doss, P. P. Srilatha, R. Nigar sulthana and Kezia Lakshmi bai (2008). Effect of cytomethrin on selective biochemical parameters in a fish Heteroneustes fossilis. Aquacult. Vol 9(2):179-184.
- Narasimha Rao, C., Rajendra Prasad, S., Jacob Doss, P. (2009). Effect of corticosterone on
silkworm larvae, Bombyx mori with special reference to economic parameters. Biosciences,
Biotechnology Research Asia. Vol.6 (1), 413-415.
- A , and P.Jacob Doss (2009). Protein metabolic profile and histopathological studies in heart tissue of rats during cypermethrin toxicosis. Toxicol.Int.vol.16, (2):91-95.
- A, and Jacob Doss .P (2009). Cypermethrin induced alterations in protein metabolic profiles in liver tissue of albino rats. The Bioscan 4 (1):25:29.
- Jacob Doss, p., Nissarahmed, G., Mohan Krishna, V., Kishore, S. Vijayakumari, K., and Rajeswara Rao, M. (2009). Inhibition of rat brain nitric oxide synthase activity by cationic amphipholic drugs in Vitro. I.J.Com.Animal physiology Vol.27(1).17-22.
- Rajeswari, I.S.R, Nagarjuna,A, Udayakumar, M and Jacob doss (2009). Toxicity evaluation of Acephate on albino rats. J. Natcon.21, 129-135.
- Ravisekhar,P. Savithri,Y. Kishore,S. Jacob doss and Jayantha Rao,K.(2009). Effect of cypermethrin on total carbohydrates, glycogen, pyruvate and lactic acid contents inliver and kidney tissues of albino rats. Asian Journalof Environmental Science,4(1):24-28.
- Rajendra Prasad, S. Nagarjuna, A, Sreedevi,C. Jacob doss.P. (2009).Alterations of protein associated enzyme systems induced by chlorpyrifos in albino rats. The Bioscan,4(1):97-100.
- Rajendra Prasad,S .Sreedevi,C. Narasimha Rao,C. Nagarjuna,A and P.Jacob doss. (2009). Impact of Chlorpyrifos on protein metabolism of albino rats. Indian Journal of Environmental Sciences 13(1)33-36.
- Siraj Mohiyuddin,S. and P.Jacob doss (2009). Acephate induced alterations in Acetylcholine and acetyl cholinesterase of different brain regions of albino rat. Journal of Indian Society of Toxicology.5(1):6-11.
- Nagarjuna,A. Rajendra Prasad,S.Savithri,Y. Sirajmohiyuddin and Jacob doss,(2009). Cypermethrrin effect on protein metabolic profiles in rat kidney. The Asian Journal of AnimalScience, Vol.3(2):179-183.
- SirajMohiyuddin and P.Jacob doss (2009). Acephate induced ixidative stress in different brain regionsofalbiono rats. Porceedingsof the International symposium on Environment Pollution, Ecology and Human health. 93-97.
- Rajendra Prasad,S. S. Nagarjuna, A. Sirajmohiyuddin,S. Ravi Sekhar,P. P. Jacb doss (2009). Alterations of cholinergic aspects during the development of behavioral tolerance to chlorpyrifos toxicity in albiono rats. Asian Jr. ofMicrobiol. Biotech. Env.Sc. Vol 11 No.(3)657-660.
- Siraj Mohiyuddin,S Rajeswara Reddy ,S.and P. Jacob doss (2009). Acephate induced Ultrastructural changes different brain regions of albino rat. The Bioscan 4(4):573-576.
- Siraj Mohiyuddin S, Rajeswara Reddy S, AnandaKumar, L and P. Jacob doss (2009).Acephate induced alterations in Mg+2ATPase and Na+K+ATPasesof different brain regions of albino rats. The Ecoscan Journal.3 (3).
- Siraj Mohiyuddin, S. AnandaKumar, L. Ramesh,P. Vasumathi Reddyand P. Jacob doss , (2009). Alterations in cytoarchitecture of different brain regions of albino rats exposed to acephate. Indian Indian Journal of comparative animal physiology. Vol 7(2):1 13-118.
- Nagarjuna, A and P.Jacob Doss, (2009) Acute oral toxicity andhistopathological studies of. Cypermethrin in rats. Indian Journal of Animal Research.43 (4):235-240.
37(a) Suseela, M., Gokul, K., Jayantha Rao, K., Jacob Doss, P., (2009).Estimation of toxicity
evaluation (LD50) of lambda cyhalothrin, a synthetic pesticide onj Albino Mice. Advanced
research journal of biological sciences and molecular techniques. Vol 1 Issue 1.
- Savithri, Y., P. Ravi Sekhar and P. Jacob Doss (2010). Changes in Hematological profiles of albino rats under chlorpyrifos toxicity. International Journal of Pharma. and Bio. Sciences. 1 (3):1-7.
- Savithri, Y., Ravi Sekhar, P., Madhava Rao, S., Kishore, S and P.Jacob Dos (2010). Effect of Organophosphorus pesticide chlorpyrifos on Ammonia and Urea levels in Albino rats. Indian Journal of Comparative Animal Physiology.Vol.28(1):102-107.
- Savithri, Y., P. Ravi Sekhar, K. Usha Rani and P. Jacob Doss (2010). Impact of chlorpyrifos on Transaminases, Total proteins and Free Amino Acids in muscle and Heart tissues of Albino rats. Journal of Experimental Zoology of India. Vol 13(2):463-467.
- Ananda Kumar.L, Siraj Mohiyuddin.S,Jacob Doss.P.(2010).Consumption of Super vasmol poison and its effect on human lungs.Acase report.Indian Journal of Forensic Medicine Toxicology.Vol.4.(2).pp.115-116.
- Nagarjuna A, Jacob Doss P (2010).Cypermethrin-induced Histochemical Changes in Liver of Albino Rats.Journal of the Indian society of Toxicology.Vol 6(2).pg 1-5.
- Nagarjuna A, and Jacob Doss. P (2010). Protein metabolic profile and Ultrastructural Studies in rat liver During cypermethrin toxicosis., J. Appl.Anim. Res.37(2010):93-98.
- Savithri Y. Ravi sekar P, Jacob Doss P (2010). Bio chemical and Histopathological changes in Liver due to Chlorpyrifos Toxicity in Albino Rats. Journal of the Indian Society of Toxicology. Vol 6(2) pg.5-10
- Narasimha Rao, C. SreeDevi, S.Rajendra Prasad,Y.Savithri, I.I.S.R. Rajeswari, S Siraj Mohiyuddin and P.Jacob Doss.(2010) Influence of Corticosterone on protein metabolism of Silkworm Larvae Bombyx Mori.Ind.Acad. Seri. Vol. 14(1) 2010.
45(a) Jayasudha M, Rajendra singh M, Devisri lakshmikala S, Ravikanth S.V, and Jacob Doss
P.(2012) Alterations in the cholinergic mechanisms in different regions of the brain of Lambda
Cyhalothrin exposed Swiss Albino Mice.Trends in life sciences(India) Vol 27(1):15-20.
- Ramesh Babu.K, Siva Prasad, Stafford Valentine Redden, P. Narender, S. Kishore, 2Ravikanth S.V. and Jacob Doss.P1 (2012) Alterations in the selected biochemical Parameters inAcephate treated mice. Indian Society of Comparative Animal Physiology Vol.(30).2012.Pg. 99-104
- Devi Srilakshmi Kala.S, V, Jayasudha.M, Malleswari.M, 2Ravikanth S.V. and Jacob Doss.P1 “Effect of Dimethoate on different regions of the brain in Albino rat’. Indian journal of comparative animal physiology ( 2013) .
- 1Obulpathi, 2S.V. Ravikanth and 1*P. Jacob doss (2013). Effect of synthetic pyrethroid Permethrin on cholinergic mechanisms in different regions of the brain in albino mice. Int J Pharm Bio Sci .2013 Oct; 4(4): (B) 381 – 385.(IF:0.67).
- Siva Prasad, K. Ramesh Babu, *S.V. Ravikanth, P. Narender and P. Jacob Doss (2013). Alterations in the acetyl cholinesterase activity in the brain of Albino mice exposed to acephate. The Bioscan 8(3): 1039-1041, 2013.
- Devi Srilakshmi Kala, S., Jacob Doss, P., (2013). Cytoarchetectual Changes in Cerbral Cortex
Toxicated with dimethoate albino rat. Int. j.Science and research.6(14).
- Sukanya, N. and Doss, p.j.(2013). Neurotoxic effects of cypermethrin in wistar strain rats: detoxification mechanisms. CIBTech Journal of Zoology ISSN: 2319-3883 PP.37-43.
- Penchalamma, Ramesh Babu. K and Jacob Doss. P (2014). Dimethoate induced oxidative stress in heart albino rat. Indian Streams Research Journal,Vol. IV, Issue. I Pg No: 1-3.(IF:2.15)
- R., Devi Sri lakshmikala and Jacob Doss. P (2014).Toxicity evaluation of dimethoate on albino rats. Golden Research Thoughts, Volume-3 | Issue-8 | Feb- 2014.(IF:2.2)
- V. Sri kanth.M. Jayasudha. M. Ravikanth. S.V. and Jacob Doss. P (2014). Effect of Profenofos on Thiobarbituric acid reactive substances, Scavenging Enzymes and Glutathion in the brain of Albino rat., Int Pharm Bio Sci 2014 Oct ; 5(4): (B) 586-595.
- M. Sachi devi. P. Ravikanth. S.V. Josthna. P. and Jacob Doss. P (2014).Oral toxicity study of the venom of Naja naja in Albino rat., Int Pharm Bio Sci 2014Oct ; 5(4): (B) 936-941.(IF 2.958)
- P, Malleswari. M, *Suneetha. Y, and Jacob doss.P, (2014). Effect of sublethel doss of Ethion on selected biochemiacal parameters in the kidney of Albino rat. Int J Pharma Bio Sci 2014 July; 5(3): (B) 804-808, (IF 2.958).
- Penchalamma, R., Ramesh Babu, K., and Jacob Doss, P. (2014). Effect of Dimethoate on the response of antioxidants in Albino rat. Science park research journal, Vol-2.Issue 18. (IF 1.6200).
- Rajendra singh, M. Malleswari, M. Babu, C. Ramadevi, CH. Jayasudha, M and Jacob Doss, P.
(2014). Profenofos induced Oxidative stress in different tissues of albino rat. Trends in Life Sciences (India) 2014, 29(1&2): 53-68
- Rajendra singh, M. Malleswari, M. Babu, C. Saradha, P. Jayasudha, M and Jacob Doss, P. (2016). Alterations of Protein associated enzyme systems induced by profenofos in albino rat.
Trends in Life Sciences (India) 2014, 29(1&2): 75-96
- M, Josthna. P. and Jacob Doss. P (2015).Orally administered venom of Naja naja alters protein metabolic profiles in the liver of Albino rats. Int J Life Sci Biotech and Pharma volume 4, No.1, January, 2015. (IF 1.009).
- Rajendra singh.M, Sreekanth. M, Jayasudha. M, Ravikanth. S.V, and Jacob Doss P. (2015). Influence of Profenos on Selected Biochemical Parameters in the Liver of Albino rat. Int Pharm Bio Sci 2015 Jan; 6(1): (b) 826-831. (IF 2.958).
- R, and Jacob Doss. P. (2015). Alteration in Protein Metabolic Profiles in Liver Tissue of Rats during Dimethoate Toxicosis. Published in IOSR Journal of Environmental Science, Toxicology and Food Technology, Vol.9, Issue 1, January.(IF 1.823)
- Devisrilakshmikala, S., Penchalamma, R., Sivaprasad, M., Jacob doss, P. (2015). Histological
alternations in cerebellum treated with dimethoate in albino rat. weekly Science Research
Journal ISSN 2321-8045.
- Malleswari M., Josthna P., and Jacobdoss P. (2015). Snake Naja Naja venom effect in albino rat, a study of renal physiology.IJU Pharmacy and Bio Sciences 4(6): 2319-8141.
- Jacob doss P., Stafford V Redden., Malleswari M., Babu C., Rajendrasingh M., and Jayasudha M. (2015). Influence of Snake Naja Naja venom on the mitochondrial ATPases in the brain of albino rat. Indian Journal of Comparative Animal Physiology.Vol.33.pg.47-56.ISSN 0255-7150.
- Malleswari M, Josthna P, and Jacobdoss P. (2015). Snake naja naja venom effect in albino rat, a study of renal physiology. International Journal of Universal Pharmacy and Bio Sciences. Vol4(6):2015
- Malleswari M., Josthna P., and Jacobdoss P. (2016). Influence of snake Naja Naja venom on DNA damage in albino rat. J.of Med. Sc. & Pharm. Res.,ISSN 2394-8973.
- Malleswari M., Josthna P., and Jacobdoss P. (2016). Insilco Three Dimensional Modeling of Ribosome Binding Factor A of Haemophilus influenza IJCSME- SCSMB-ISSN-2349-8439.
- jacob doss p*, Stafford V Redden, Malleswari M, Rajendrasingh M, Jayasudha M, and C Babu (2016). Snake Naja Naja venom effect on the cholinergic aspects in different brain regions of the albino rat. Indian Journal of Comparative Animal Physiology. Vol.34 (2016) p.75-84.
- Rajendra Singh M., Malleswari M., Babu C., Ramadevi CH., and P Jacob Doss (2017). Profenofos induced effect on liver and kidney tissues in albino rat. Indian Journal of Comparative Animal Physiology. Vol.35 (2017) p.47-56.
- Babu C., Rajendra Singh M., Sachidevi P., Ramadevi CH., Ravikanth SV, and P Jacob Doss (2018). Thiodicarb induced oxidative stress in different tissues of Albino Rat. Indian Journal of Comparative Animal Physiology. Vol.36 (2018) p.19-27.
- Babu C., Sachidevi P., Rajendra Singh M., Ravikanth SV, and P Jacob Doss (2018). Protein metabolic profiles of carbamate compound Thiodicarb influences in Albino Rats. Indian Journal of Comparative Animal Physiology. Vol.36 (2018) p.82-92.
- Ramadevi Ch., Babu C., Sarada P., Usharani K., Mahammad Ismail T., Jayasudha M., Ravikanth SV., Monika B and P. Jacob Doss. (2019). Alterations in the acetylcholinesterase activity in different regions of the brain exposed to sub lethal concentration of carbamate, thiodicarb. Indian Journal of Comparative Animal Physiology. Vol.37 (2019) p.6-10.
- Ramadevi Ch., Babu C., Usharani K., Mahammad Ismail T., Sarada P., Jayasudha M., Ravikanth
and P. Jacob Doss. (2019). Thiodicarb Induced Changes in the Detoxification Enzymes in the Brain of Albino Rat. Indian Journal of Comparative Animal Physiology. Vol.37 (2019) p.15-26.
- Sarada P., Babu C., Jayasudha M., Ramadevi ch., Rajendra Singh M., Usharani K., Prasanna ,and P. Jacob Doss (2020). Dimethoate Provokes Oxidative Stresson Different Brain regions of Albino Mice. Indian Journal of Comparative Animal Physiology. Vol.38 p.1-10. ISSN 0255-7150.
- Sarada P., Jayasudha M., Babu C., Ramadevi ch., Rajendra Singh m., and P. Jacob Doss (2020). Dimethoate Exposed Acetylcholinesterase Activity in The Brain of Albino Mice.Indian Journal of Comparative Animal Physiology. Vol.3818-24. ISSN 0255-7150.
- Vijaya G., Vimala K., Monika , Prasanna B., Sailaja T., and P . Jacob Doss (2020). Effects of Sodium Arsenate on Different Tissues of Albino Mice . Indian Journal of Comparative Animal Physiology. Vol.38 (2020). p.41-46. ISSN 0255-7150.
Books
Research interest
Arachnid Neurobiology; Neurotoxicology and Neuroethology